Anti-人CD43 Pacific Blue(流式抗體)-Anti-Hu CD43 Pacific Blue代理/參數(shù)/廠家-一抗-艾美捷科技有限公司

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背景資料: CD43 (leukosialin, sialophorin) is a transmembrane mucin-like protein with high negative charge, expressed on the surface of most hematopoietic cells. CD43 contributes to a repulsive barrier that interferes with cellular adhesion, however, in certain cases also promotes leukocyte aggregation. By interaction with actin-binding proteins ezrin and moesin CD43 plays a regulatory role in remodeling T-cell morphology and regulates cell-cell interactions during lymphocyte traffic. CD43 signaling both enhances LFA-1 adhesiveness and counteracts LFA-1 induction via other receptors. Expression of CD43 causes induction of functionally active tumour suppressor p53 protein, but in case of p53 and ARF defficiency CD43 promotes tumour proliferation and viability. It appears to be an important modulator of leukocyte functions.

保存建議: Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.

其他: EXBIO是捷克一家著名的生物試劑公司，專注于流式細胞術(shù)配套試劑的開發(fā)。自1990年成立以來，EXBIO公司研發(fā)和制造的抗體分銷全球。目前，EXBIO可提供超過4000種質(zhì)優(yōu)、價廉的研究和臨床應(yīng)用抗體，涵蓋了血液學，免疫學，癌癥，干細胞和細胞生物學等領(lǐng)域，如：CD分子、細胞粘附分子、細胞骨架、凋亡、細胞信號傳導(dǎo)、腫瘤標志物、人血型、HLA、生殖等研究用抗體，涉及熒光染料如FITC、PE、PE-Cy5、PE-Cy7、APC、PerCP、PerCP-Cy5.5、Pacific Blue、Pacific Orange、Alexa Fluor 488、Alexa Fluor 647、Alexa Fluor 700、Biotin等多達13種，滿足客戶各類實驗需求。