The GABA-A receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (1). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (2). Recent research shows their usage in investigating side effects of drugs and the effects of learning and memory. Inverse agonists of the A5 subunit may be useful in the treatment of Alzheimer's Disease (3).
StressMarq Biosciences Inc. 在2007年成立于加拿大維多利亞,是一家生物科技公司,專門從事試劑與試劑盒研究,服務范圍遍及全714多個國家。 StressMarq公司的核心技術領域為細胞應激(尤其是熱休克蛋白(HSP)領域,領先全球),離子通道,載體研究,同時在神經(jīng)科學領域推出特有的具有生物活性的Tau蛋白與A-突觸核蛋白。產(chǎn)品領域涉及到:細胞凋亡、細胞信號、通路和轉(zhuǎn)運、細胞器標志物、熱休克、神經(jīng)生物學、神經(jīng)科學、氧化應激、磷酸化運輸?shù)取3颂峁┯糜谶M一步研究的相關工具外,Str