Tissue inhibitors of metalloproteinases, or TIMPs are members of the family of tissue inhibitors of matrix metalloproteinases (MMPs). They exhibit multiple functions, including the inhibitory effect on MMPs, but they also they irreversibly inactivate MMPs by direct binding to their catalytic zinc cofactor and resultant inhibition of proteinase function. In addition they interact with various membrane receptors on the cell surface. TIMP1 in particular interacts with CD63. TIMPs are involved in a wide variety of biological functions, such as tumor angiogenesis and progression, wound healing, and vascular remodeling.
應用類型
WB | ELISA
免疫原
人 TIMP1內段合成肽.
來源宿主
兔
反應性
人 | 小鼠 | 大鼠
保存建議
廠家推薦藍冰運輸。收到產品后建議保存于-20oC。
其他
StressMarq Biosciences Inc. 在2007年成立于加拿大維多利亞,是一家生物科技公司,專門從事試劑與試劑盒研究,服務范圍遍17002多個國家。 StressMarq公司的核心技術領域為細胞應激(尤其是熱休克蛋白(HSP)領域,領先全球),離子通道,載體研究,同時在神經科學領域推出特有的具有生物活性的Tau蛋白與A-突觸核蛋白。產品領域涉及到:細胞凋亡、細胞信號、通路和轉運、細胞器標志物、熱休克、神經生物學、神經科學、氧化應激、磷酸化運輸?shù)取3颂峁┯糜谶M一步研究的相關工具外,Str????廚?????坊?????????????◢???軈?se