轉(zhuǎn)化生長因子B3抗體-TGF beta 3 Antibody: Dylight 405代理/參數(shù)/廠家-一抗-艾美捷科技有限公司

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背景資料: Transforming growth factor B-3 is a protein that in humans is encoded by the TGFB3 gene. It is a membrane proteoglycan that often functions as a co-receptor with other TGF-B receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. TGFBR3 is extensively modified by glycosaminoglycan groups (GAG). TGF-B3 is believed to regulate molecules involved in cellular adhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF-B3, mammals develop a deformity known as a cleft palate. This is caused by failure of epithelial cells in both sides of the developing palate to fuse.

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