TNF receptor-associated factor 6 is a member of the TNF receptor associated factor (TRAF) protein family. TNF receptor-associated factor 6 proteins play an important role as adaptor protein for cell survival, proliferation, differentiation and stress responses. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. Two alternatively spliced transcript variants encoding identical proteins have been reported.
應用類型
WB | IHC
免疫原
人 TRAF6合成肽
來源宿主
兔
反應性
人 | 小鼠 | 大鼠
保存建議
廠家推薦藍冰運輸。收到產(chǎn)品后建議保存于-20oC。
其他
StressMarq Biosciences Inc. 在2007年成立于加拿大維多利亞,是一家生物科技公司,專門從事試劑與試劑盒研究,服務范圍遍17625多個國家。 StressMarq公司的核心技術領域為細胞應激(尤其是熱休克蛋白(HSP)領域,領先全球),離子通道,載體研究,同時在神經(jīng)科學領域推出特有的具有生物活性的Tau蛋白與A-突觸核蛋白。產(chǎn)品領域涉及到:細胞凋亡、細胞信號、通路和轉運、細胞器標志物、熱休克、神經(jīng)生物學、神經(jīng)科學、氧化應激、磷酸化運輸?shù)取3颂峁┯糜谶M一步研究的相關工具外,Str????廚?????坊?????????????◢???軈?se