糖原合成酶激酶-3B 抗體-GSK-3beta Antibody: Dylight 488代理/參數(shù)/廠家-一抗-艾美捷科技有限公司

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背景資料: Glycogen synthase kinase 3, is a serine/threonine protein kinase that mediates the addition of phosphate molecules onto serine and threonine amino acid residues.? It has also been shown to regulate immune and migratory processes, and is tied to pathways of cell proliferation and apoptosis (1-3). In mammals, it is encoded by two genes- GSK-3A and GSK-3B. They are structurally similar, but functionally non-identical. GSK-3A is inhibited by phosphorylation at S21 by Akt and other kinases. GSK-3B negatively regulates cardiac hypertrophy and cardiac development through its effect on WNT signaling (4). GSK-3 A and GSK-3 B share 85% amino acid identity. GSK-3 has been implicated in a number of diseases including Type II diabetes, Alzheimer’s, cancer and bipolar (4, 5).

其他: StressMarq Biosciences Inc. 在2007年成立于加拿大維多利亞，是一家生物科技公司，專門從事試劑與試劑盒研究，服務(wù)范圍遍及3083多個(gè)國(guó)家。 StressMarq公司的核心技術(shù)領(lǐng)域?yàn)榧?xì)胞應(yīng)激（尤其是熱休克蛋白（HSP）領(lǐng)域，領(lǐng)先全球），離子通道，載體研究，同時(shí)在神經(jīng)科學(xué)領(lǐng)域推出特有的具有生物活性的Tau蛋白與A-突觸核蛋白。產(chǎn)品領(lǐng)域涉及到：細(xì)胞凋亡、細(xì)胞信號(hào)、通路和轉(zhuǎn)運(yùn)、細(xì)胞器標(biāo)志物、熱休克、神經(jīng)生物學(xué)、神經(jīng)科學(xué)、氧化應(yīng)激、磷酸化運(yùn)輸?shù)取３颂峁┯糜谶M(jìn)一步研究的相關(guān)工具外，Str