- 中文名稱
Anti-IFN gamma PE-Cy 7(流式抗體)
- 英文名字
- Anti-IFN gamma PE-Cy 7
- 供應(yīng)商
- EXBIO
- 產(chǎn)品貨號(hào)
- T7-706-T025
- 產(chǎn)品報(bào)價(jià)
- ￥已停產(chǎn)
- 產(chǎn)品說明書
- 點(diǎn)擊查看
- 購買方式
- 銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868。
- 產(chǎn)品新聞
- 背景資料
- The Interferon gamma (IFN-gamma; 16-25 kDa) is an important regulator of the immune response, produced in activated Th1 cells and NK cells, particularly in response to IL-2, TNF-alpha and IL-12; its production is suppressed by IL-4, IL-10, and TGF-beta. The producing of IFN-gamma is activated by specific antigens or mitogens through the T cell antigen receptor. IFN-gamma polypeptide forms: 40-60 kDa forms are observable under non-denaturing conditions as dimers and trimers; 20 kDa and 25 kDa forms exist due to variable glycosylation. IFN-gamma belongs to the type II interferons, also called immune IFN. IFN-gamma shows antiviral activity and has important immunoregulatory functions. It is a potent activator of macrophages and had antiproliferative effects on transformed cells. IFN-gamma plays an important role in regulating B cell differentiation by simultaneously stimulating class switch recombination to the IgG3 and IgG2a isotypes while represing class switch recombination to the IgE and IgG1 isotypes. It also appears to promote antigen presentation by B cells through its effects on MHC. Binding of IFN-gamma to its receptor increases the expression of class I MHC on all somatic cells. It also enhances the expression of class II MHC on antigen-presenting cells. IFN-gamma is the major means by which T cells activate macrophages, increasing their ability to kill bacteria, parasites, and tumours. The activation of macrophages by IFN-gamma is essential for the elimination of bacteria that replicate within the phagosomes of macrophages (f.e. Mycobacteria and Listeria monocytogenes). IFN-gamma can potentiate the high antiviral and antitumor effects of the type I interferons (IFN-alpha, IFN-beta). IFN-gamma may also activate neutrophils and NK cells.
- 應(yīng)用類型
- FC (QC tested)
- 免疫原
- Interferon gamma derived from human leukocytes
- 來源宿主
- 小鼠
- 反應(yīng)性
- Non-human primates, Human
- 保存建議
- Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
- 其他
- EXBIO是捷克一家著名的生物試劑公司，專注于流式細(xì)胞術(shù)配套試劑的開發(fā)。自1990年成立以來，EXBIO公司研發(fā)和制造的抗體分銷全球。目前，EXBIO可提供超過4000種質(zhì)優(yōu)、價(jià)廉的研究和臨床應(yīng)用抗體，涵蓋了血液學(xué)，免疫學(xué)，癌癥，干細(xì)胞和細(xì)胞生物學(xué)等領(lǐng)域，如：CD分子、細(xì)胞粘附分子、細(xì)胞骨架、凋亡、細(xì)胞信號(hào)傳導(dǎo)、腫瘤標(biāo)志物、人血型、HLA、生殖等研究用抗體，涉及熒光染料如FITC、PE、PE-Cy5、PE-Cy7、APC、PerCP、PerCP-Cy5.5、Pacific Blue、Pacific Orange、Alexa Fluor 488、Alexa Fluor 647、Alexa Fluor 700、Biotin等多達(dá)13種，滿足客戶各類實(shí)驗(yàn)需求。
- 注意
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該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請(qǐng)以廠家的英文說明書為準(zhǔn)。下單前，請(qǐng)瀏覽說明書確認(rèn)。
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