Anti-人CD45 PerCP-Cy 5.5(流式抗體)-Anti-Hu CD45 PerCP-Cy 5.5代理/參數(shù)/廠家-一抗-艾美捷科技有限公司

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背景資料: CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing; these isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. Besides the role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis.

保存建議: Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.

其他: EXBIO是捷克一家著名的生物試劑公司，專注于流式細(xì)胞術(shù)配套試劑的開發(fā)。自1990年成立以來，EXBIO公司研發(fā)和制造的抗體分銷全球。目前，EXBIO可提供超過4000種質(zhì)優(yōu)、價(jià)廉的研究和臨床應(yīng)用抗體，涵蓋了血液學(xué)，免疫學(xué)，癌癥，干細(xì)胞和細(xì)胞生物學(xué)等領(lǐng)域，如：CD分子、細(xì)胞粘附分子、細(xì)胞骨架、凋亡、細(xì)胞信號傳導(dǎo)、腫瘤標(biāo)志物、人血型、HLA、生殖等研究用抗體，涉及熒光染料如FITC、PE、PE-Cy5、PE-Cy7、APC、PerCP、PerCP-Cy5.5、Pacific Blue、Pacific Orange、Alexa Fluor 488、Alexa Fluor 647、Alexa Fluor 700、Biotin等多達(dá)13種，滿足客戶各類實(shí)驗(yàn)需求。